Conceptual illustration of molecular drug discovery, showing a computer, protein structures and a small molecule.

PROSTATE CANCER RESEARCH · VANCOUVER, CANADA

Understanding cancer.Advancing discovery.

We study how cancer cells adapt to treatment—and how that knowledge can guide new therapeutic strategies.

Conceptual research illustration

THE DONG LAB

From molecular questions to new possibilities.

Led by Dr. Xuesen Dong, our laboratory at the Vancouver Prostate Centre investigates the mechanisms that drive treatment resistance in prostate cancer. We bring together RNA biology, cancer research and computer-aided drug discovery to identify new ways to understand and target resistant disease.

Meet Dr. Xuesen Dong

OUR RESEARCH

Three connected directions.

Understanding cancer at the molecular level helps us ask better questions about detection and treatment.

RNA biology & treatment resistance

We investigate how RNA-binding proteins and RNA regulation influence prostate cancer progression and the ability of tumour cells to adapt to therapy.

RNA regulation · Cancer progression

Computer-aided drug discovery

We connect computational approaches with experimental research to identify and study compounds that target cancer-associated molecular processes.

Molecular targets · Therapeutic discovery

Biomarkers & disease insight

We explore RNA-based biomarkers, including circular RNAs, to better understand prostate cancer and investigate opportunities for diagnosis.

Circular RNA · Biomarker research

Conceptual research illustration of a pipette, a culture dish and molecular structures.
Conceptual research illustration

OUR APPROACH

Discovery begins with a question.

Why do tumours become resistant to treatment? Which molecular processes can we target? We investigate these questions by connecting computational analysis with laboratory experiments.

  1. Understand the biology
  2. Identify a molecular opportunity
  3. Test the hypothesis

CONNECT WITH US

Let's move discovery forward.

Interested in our research, collaboration or training? Contact Dr. Xuesen Dong to start a conversation.

Email the lab
Dr. Xuesen Dong

Professor, UBC · Senior Scientist, Vancouver Prostate Centre

xdong@prostatecentre.com

Vancouver, British Columbia, Canada

View institutional profile